Platelet-Rich Plasma vs. Hyaluronic Acid for Hip Osteoarthritis: Minimum 12-Month Follow-Up Results

Hyaluronic acid (HA) and platelet-rich plasma (PRP) are two non-operative treatment options for patients with early hip osteoarthritis (OA). The purpose of this study was to compare the efficacy intra-articular injections HA PRP in OA. Patients presenting a preservation surgeon signs OA were randomized or PRP. Each patient received 3 at 1-week intervals either followed minimum 12-months. primary outcome, survivorship, analyzed by investigating frequency withdrawal undergo surgery (total arthroplasty (THA) resurfacing). Western Ontario McMaster Universities Osteoarthritis Index (WOMAC) score range motion secondary outcomes. Twenty-eight (57.1% male) 30 hips (hips, HA=13; PRP=17) included. Two (one per group) underwent bilateral hips. Average age time first injection 54 years. Significantly more withdrew THA resurfacing who (6/13, 46.2%; mean, 1.5 years following injection) than (1/17, 5.9%; 1.1 (p=0.043). There no significant improvements declines any outcome among group from pre-injection 6 weeks, 3, 6, 12 months. For group, WOMAC function (p=0.040) scores significantly improved weeks. Compared demonstrated greater weeks (p=0.039) function. When comparing difference months between groups, improvement joint (p=0.0030) (p=0.0057), while showed decline scores. pain months, both groups' declined, but compared (p=0.019). internal rotation (IR) 90 degrees flexion an increase IR decrease (p=0.021). within Intra-articular result symptomatic delay need procedure HA. Further is needed determine population.